Welcome To Environmental Toxicology Lab
Southern Illinois University-Edwardsville
Department of Environmental Sciences
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Mailing Address
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Dept. of Environmental Sciences
2180 Science West Building
Southern Illinois University-Edwardsville
Edwardsville, IL 62026. USA
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Fax:
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618-650-5102
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Phone:
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Office: 618-650-3302
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Email:
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Research
Interests
My main research interests span a spectrum of environmental toxicology and medical entomology to protect agriculture, animal and human health in environmentally safe, sustainable and affordable ways. I have been particularly interested in the following areas of interdisciplinary research: (1) mechanism of acute action of toxic substances: (2) genetic and epigenetic factors and processes associated with insecticide resistance; (3) adverse effects of sub-lethal and long-term exposure to environmental chemicals; (4) controlling and management of human head and body louse populations; and (5) developing and evaluating biochemical and molecular diagnostics for chemical and pest management. Overall, my scholarly work has attempted to addresses the linkage and interaction between exposure to environmentally ubiquitous toxic substances and factors governing physiology, genetics and epigenetics.
EDUCATION
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Ph.D., Environmental Toxicology and Risk Assessment Program, Public Health, University of Massachusetts-Amherst, 2006.
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M.S., Entomology, University of Massachusetts-Amherst, 2001.
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B.S., Environmental Sciences, University of Massachusetts-Amherst, 1997.
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POSITION HELD
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2020-present Associate Professor, Department of Environmental Sciences, Southern Illinois University-Edwardsville
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2017-present Adjunct Professor, Department of Biological Sciences, SIUE
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2017-2020 Assistant Professor, Department of Environmental Sciences, SIUE
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2014-2017 Assistant Professor, Department of Biological Sciences and Environmental Sciences Program, SIUE
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2012-2014 Senior Research Fellow/Lab Manager, Department of Veterinary and Animal Sciences, UMASS
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2011-2012 Lecturer (part-time, spring semester) Environmental Science Program, Department of Environmental Conservation, UMASS
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2009-2013 Adjunct Assistant Professor Environmental Science Program, Department of Environmental Conservation, UMSS
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•2006-2012 Post-doctoral Research Associate/Lab Manager, Department of Veterinary and Animal Sciences, UMASS
Kyong Sup Yoon, Ph.D.
Principal Investigator
PEOPLE
Lalita Mazgaeen
Master degree
Former student
University of Iowa
Yousuf Ali
Master degree
Former student
Texas Tech University
Ki-Bae Hong, Ph.D.
Former Postdoc
Tel: 208-596-1438
SELECTED RESEARCH ARTICLES
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Kim, J. H., Moreau, J. A., Ali, Y., Razo, P., Hong, K. -B., Yoon, K. S., Clark, J. M. (2018) RNAi validation of detoxification genes involved in ivermectin tolerance in Drosophila melanogaster. Insect Mol. Biol. 27:651-660.
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Kim, J., Park, M. Y., Kim, Y., Yoon, K. S., Clark, J. M., Park, Y., Whang, K. -Y. (2017) 4,4’-Dichlorodiphenyltrichloroethane (DDT) and 4,4’-dichlorodiphenyldichloroethylene (DDE) inhibit myogenesis in C2C12 myoblasts. J. Sci. Food Agric. 97:5176-5185.
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Sun, Q., Qi, W., Xiao, X., Yang, S. -H., Kim, D., Yoon, K. S., Clark, J. M., Park, Y. (2017) Imidacloprid promotes high-fat diet-induced adiposity and female C57BL/6J mice and enhances adipogenesis in 3T3-L1 adipocytes via the AMPKa-mediated pathway. J. Agric. Food Chem. 65:6572-6581.
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Xiao, X., Kim, Y., Kim, D., Yoon, K. S., Clark, J. M., Park, Y. (2017) Permethrin alters glucose metabolism in conjunction with high fat diet by potentiating insulin resistance and decreases voluntary activities in female C57BL/6J mice. Food Chem. Toxicol. 108:161-170.
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Kim, J. H., Previte, D. J., Yoon, K. S., Murenzi, E., Koehler, J. E., Pittendrigh, B. R., Lee, S. H., Clark, J. M. (2017) Comparison of the proliferation and excretion of Bartonella quintana between body and head lice following oral challenge: Insights into the vector competence difference. Insect Mol. Biol. 26:266-276.
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Bowles, V. M., Yoon, K. S., Barker, S. C., Tran, C., Rhodes, C., Clark, J. M. (2017) Ovicidal efficacy of abametapir against eggs of human head and body lice (Anoplura: Pediculidae). J. Med. Entomol. 54:167-172.
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Sun, Q., Xiao, X., Kim, Y., Kim, D., Yoon, K. S., Clark, J. M., Park, Y. (2016) Imidacloprid promotes high-fat diet-induced adiposity and insulin resistance in male C57BL/6J mice. J. Agric. Food Chem. 64:9293-9306.
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Kim, J., Sun, Q., Yue, Y., Yoon, K. S., Whang, K. -Y. Clark, J. M., Park, Y. (2016) 4,4’-Dichlorodiphenyltrichloroethane (DDT) and 4,4'-dichlorodiphenyldichloroethylene (DDE) promote adipogenesis in 3T3-L1 adipocyte cell culture. Pestic. Biochem. Physiol. 131:40-45.
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Gellatly, K. J., Krim, S., Palenchar, D. J., Shepherd, K., Yoon, K. S., Rhodes, C. J., Lee, S. H., Clark, J. M. (2016) Expansion of the knockdown resistance frequency map for human head lice in the USA using quantitative sequencing. J. Med. Entomol. 53:653-659.
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Sun, Q., Qi, W., Yang, J. J., Yoon, K. S., Clark, J. M., Park, Y. (2016) Fipronil promotes adipogenesis via AMPKα-mediated pathway in 3T3-L1 adipocytes. Food Chem. Toxicol. 92:217-223.